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Understanding Seronegative Polyarthralgia – Causes, Symptoms, and Physiotherapy Management at Physio360.

  • Writer: PHYSIO 360
    PHYSIO 360
  • Sep 13
  • 3 min read

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Introduction

Joint pain is a prevalent health issue that can impact individuals across all age groups. When multiple joints are painful without clear signs of autoimmune markers such as rheumatoid factor (RF) or anti-CCP antibodies, the condition is termed Seronegative Polyarthralgia. This condition often leads to diagnostic confusion, unlike seropositive arthritis, leaving patients in search of effective treatment solutions. At Physio360 Chennai, we focus on evaluating, diagnosing, and delivering advanced physiotherapy care for conditions like seronegative polyarthralgia, aiming to enhance mobility, alleviate pain, and improve overall quality of life.


What is Seronegative Polyarthralgia?

Polyarthralgia refers to pain affecting multiple joints. Seronegative indicates the lack of typical blood markers that usually signify autoimmune disorders such as rheumatoid arthritis. Patients report joint pain, stiffness, and swelling, but test negative for RF and anti-CCP antibodies. This condition is frequently associated with:

✔ Early stages of inflammatory arthritis

✔ Reactive arthritis

✔ Psoriatic arthritis

✔ Ankylosing spondylitis

✔ Viral infections or metabolic factors


Symptoms of Seronegative Polyarthralgia

Patients may encounter: Persistent joint pain in the hands, wrists, knees, ankles, or spine Morning stiffness lasting over 30 minutes Swelling or tenderness in several joints Fatigue and decreased physical activity Challenges in daily tasks such as climbing stairs, writing, or walking long distances Given that this condition resembles other forms of arthritis, a thorough evaluation by specialists at Physio360 is crucial for effective management.


Diagnosis

The diagnosis of seronegative polyarthralgia includes a comprehensive medical history and physical examination, Blood tests to exclude rheumatoid factor and anti-CCP antibodies, and Imaging studies such as X-rays or MRI to identify early joint changes. Screening for associated conditions, including psoriasis, ankylosing spondylitis, or inflammatory bowel disease, is also recommended.



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Role of Physiotherapy at Physio360

While medications help control inflammation, physiotherapy plays a vital role in long-term management and functional recovery. At Physio360 Chennai, we design personalised treatment programs to improve mobility, strength, and independence.

Physiotherapy Management Includes:

  1. Pain Relief Techniques

    • Ultrasound therapy, TENS, and hot/cold therapy to reduce joint pain and stiffness.

  2. Joint Mobilization

    • Gentle manual therapy to restore joint range of motion and prevent stiffness.

  3. Strengthening Exercises

    • Customised strengthening plans for weak muscles around the joints.

    • Focus on core stability and postural correction.

  4. Flexibility and Stretching

    • Stretching tight muscle groups to reduce stiffness and improve movement.

  5. Functional Training

    • Guidance for safe movements during walking, climbing stairs, or lifting objects.

  6. Lifestyle & Ergonomic Advice

    • Educating patients on joint protection, posture correction, and activity modification

Why Choose Physio360 for Seronegative Polyarthralgia?

At Physio360 Chennai, our physiotherapists are trained in advanced manual therapy, exercise prescription, and rehabilitation techniques. We focus not only on reducing pain but also on restoring strength, flexibility, and independence in daily activities.

✅ Personalised care plans

✅ Evidence-based treatment

✅ Modern physiotherapy modalities

✅ Friendly and supportive environment



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Conclusion

Seronegative Polyarthralgia can be a confusing and frustrating condition due to its unclear diagnostic markers, but with the right combination of medical and physiotherapy care, patients can lead an active and pain-free life. At Physio360 Chennai, we ensure holistic management that addresses both symptoms and underlying functional limitations.

If you are struggling with unexplained joint pain and stiffness, visit Physio360 Chennai for expert assessment and effective physiotherapy management.


REFERENCE AND RESEARCH ARTICLE.

1.Seronegative rheumatoid arthritis: Pathogenetic and therapeutic aspectshttps://doi.org/10.1016/j.berh.2014.10.016.


2.Is seronegative rheumatoid arthritis true rheumatoid arthritis? A nationwide cohort studyhttps://pmc.ncbi.nlm.nih.gov/articles/PMC8121445/.

 
 
 

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